Hygiene is a vital consideration when selecting a sex doll, as proper maintenance ensures safety and longevity. Inflatable dolls, typically made from PVC or similar materials, are relatively easy to clean. Their smooth, non-porous surfaces can be wiped down quickly with disinfectant wipes or mild soap and water. Since they are less complex structurally, there are fewer intricate areas where dirt or bacteria can hide, making cleaning straightforward.

Silicone dolls, valued for their realistic feel, also boast non-porous surfaces that resist bacteria buildup when properly cleaned. However, their detailed features—such as facial features, joints, and internal cavities—may require more careful and thorough cleaning. Using specialized cleaning solutions designed for silicone ensures effective sanitation without damaging the material.

Both types of dolls can be kept hygienic with regular maintenance. Inflatable dolls offer simplicity in cleaning, which might be advantageous for quick sanitation routines. Silicone dolls, while more detailed, demand meticulous cleaning to reach all crevices, but they generally provide a more durable and long-lasting hygienic surface. Ultimately, maintaining hygiene depends on consistent cleaning practices, regardless of the material, but inflatable dolls may offer a slight edge in ease of sanitation.